منابع مشابه
RIC-7 Promotes Neuropeptide Secretion
Secretion of neurotransmitters and neuropeptides is mediated by exocytosis of distinct secretory organelles, synaptic vesicles (SVs) and dense core vesicles (DCVs) respectively. Relatively little is known about factors that differentially regulate SV and DCV secretion. Here we identify a novel protein RIC-7 that is required for neuropeptide secretion in Caenorhabditis elegans. The RIC-7 protein...
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Background: Orexin A, a small-molecule peptide, can regulate female hormones, but limited evidence for its mechanism of activity exists in ovine. Aims: The objective of this study was to investigate the effect of orexin A on progesterone (P4) secretion in cultured granulosa of sheep follicles. Methods: Sheep ovarian granulosa were isolated and ...
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The actions of LHRH, CRH and NPY on the activity of the reproductive axis and, in particular, the LHRH pulse generator were investigated in vivo. A model was developed to allow direct administration of neuro¬ peptides, antagonists and antibodies into the third cerebral ventricle of conscious, free-moving and unstressed sheep, giving access to hypo¬ thalamic periventricular structures involved i...
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Odorants are detected by a large family of odorant receptors (ORs) expressed in the nose. The information provided by the ORs is transmitted to specific regions of the brain, leading to odorant perception. The determination of the odorant specificities of the different ORs will contribute to the understanding of how odorants are discriminated by the olfactory system. However, to date only a few...
متن کاملThe involvement of kisspeptin in centrally regulatory mechanism of neuropeptide Y on testosterone secretion in male Wistar rats
Introduction: Numerous studies have demonstrated that kisspeptin, a peptide from the KISS1 gene, plays an important role in regulating the secretion of gonadotropin releasing hormone (GnRH). Also, there is some evidence suggesting that kisspeptin can interact with other neuropeptides for the control of the reproductive axis. In the present study, we have investigated the effect of central admin...
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ژورنال
عنوان ژورنال: PLoS Genetics
سال: 2012
ISSN: 1553-7404
DOI: 10.1371/journal.pgen.1002464